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April 14, 1978

Medical News

JAMA. 1978;239(15):1475-1483. doi:10.1001/jama.1978.03280420011002

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Intravenous antibiotic therapy can leave hospital along with patient  Keeping patients with certain infections in the hospital for several weeks strictly for intravenous (IV) antibiotic therapy ties up expensive and scarce facilities and is frustrating to otherwise well persons.Three recent clinical trials have shown this can be avoided by training patients with (mainly) bone or joint infections or endocarditis to administer their own IV antibiotics at home or at work.Results of one trial that included 20 patients were reported at the recent meeting of the Royal College of Physicians and Surgeons of Canada by Grant Stiver, MD, assistant professor of medicine and medical microbiology at the University of Manitoba, Winnipeg. Infections included 17 cases of bacterial osteomyelitis, mostly staphylococcal, and three fungal infections. The drugs prescribed were penicillins, gentamicin, and amphotericin B.Patients were first treated with IV antibiotics in the hospital, then trained for one to