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July 10, 1981

Principles of Animal Virology

JAMA. 1981;246(2):169. doi:10.1001/jama.1981.03320020057030

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The Disorders of Cardiac Rhythm, by Leo Schamroth, 2 vol, ed 2; 736+ pp, with illus, $175, Oxford, England, Blackwell Scientific Publications (St Louis, Blackwell Mosby Book Distributors), 1980.

Is prophylactic therapy with antiarrhythmic drugs desirable for all patients with myocardial infarctions? According to Scherlag and Lazzara, in Cardiac Arrhythmias, the verdict is still out. They note, however, that premonitory ectopic complexes may not precede serious arrhythmias. Nor is electroversion without risk. Resnekov, who describes its techniques and indications, cites the raised serum enzyme levels that follow application of high-energy electrical currents. Like the other contributors to Dr Mandel's book, he relies on data from the electrophysiological laboratory to illustrate his discussions.

Baurenfeind and colleagues tell how electrophysiological studies clarify the mechanisms of supraventricular tachycardia. They usually prefer the treatment that increases refractoriness in a reentrant pathway. Antiarrhythmic drugs that are compared by Singh and Mandel include verapamil, aprindine, and