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February 3, 1975

Myocarditis in Mycoplasma pneumoniae Pneumonia: Occurrence With Hemolytic Anemia and Extraordinary Titers of Cold Isohemagglutinins

Author Affiliations

From the Department of Medicine, Hutzel Hospital Unit, Department of Medicine, Wayne State University School of Medicine, Detroit.

JAMA. 1975;231(5):493-494. doi:10.1001/jama.1975.03240170035015

INFECTIONS with Mycoplasma pneumoniae have infrequently been associated with myopericarditis.1 We recently treated a 20-year-old college student with severe M pneumoniae pneumonia involving four lobes of the lungs. In the third week of his illness, he developed myopericarditis requiring coronary unit care. Simultaneously, hemolysis and unprecedented high titers of cold hemagglutinins occurred.

Report of a Case  A 20-year-old college student became ill on Nov 15, 1973. Symptoms included headache, fever, chills, pleurisy, and nonproductive cough. Chest x-ray film showed bilateral pneumonia involving right upper and middle and both lower lobes. He was admitted to Cottage Hospital in Grosse Pointe, Mich. Hemoglobin value was 14.2 gm/100 ml, and white blood cell (WBC) count was 4,900/cu mm, with a shift to the left and toxic granules within neutrophils. Although the patient received a variety of antibiotics (penicillin G potassium, ampicillin sodium, carbenicillin disodium, and gentamicin sulfate), his condition did not improve.