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July 24, 1981

Fatal Syncytial Virus Pneumonia in a Laminar Airflow Room

Author Affiliations

From the Departments of Medicine (Dr Crane) and Oncology (Drs Kish and Ratanatharathorn), Wayne State University School of Medicine, and the Departments of Pathology, Children's Hospital of Michigan (Dr Merline) and Harper-Grace Hospitals (Dr Raval), Detroit.

JAMA. 1981;246(4):366-368. doi:10.1001/jama.1981.03320040038028

A rapidly progressive, fatal pneumonia occurred during the third week of hospitalization in an immunosuppressed man confined in a laminar airflow room. Respiratory syncytial virus was isolated from open lung biopsy tissue. Epidemiologic data suggested that the virus was community acquired. Respiratory syncytial virus should be considered in the differential diagnosis of pneumonia in severely immunocompromised adults.

(JAMA 1981;246:366-368)