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May 12, 1978

Preclinical Hemochromatosis in a Population on a High-Iron-Fortified Diet

Author Affiliations

From the Departments of Medicine (Dr Olsson) and Clinical Chemistry (Dr Heedman), Oestersund Hospital, Sweden and Rural District Medical Centre (Dr Staugȧrd), Hede, Sweden.

JAMA. 1978;239(19):1999-2000. doi:10.1001/jama.1978.03280460067021

Three hundred forty-seven (96.4%) of all persons aged 30 to 39 years were screened with serum iron and iron binding capacity measurements to determine the incidence of hemochromatosis in a population. No women had signs of iron overload; however, nine men (5%) had persistently elevated serum iron levels. In four men (2%), increased iron stores was found with a distribution like that in the early stages of hemochromatosis. In combination with recent findings of clinical hemochromatosis at our hospital, this study suggests that this condition is not as rare as has been reported earlier.

(JAMA 239:1999-2000, 1978)