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July 21, 1978

lododerma From Wound Irrigation With Povidone-lodine

Author Affiliations

From the Dermatology Service, Wilford Hall US Air Force Medical Center, Lackland Air Force Base, San Antonio, Tex.

JAMA. 1978;240(3):249-250. doi:10.1001/jama.1978.03290030067028

IODODERMA is a protean group of skin lesions that includes urticarial lesions, acneiform papules and pustules, vesicles, bullae, vegetating lesions, nodules, and tumors. It is usually induced by the ingestion of iodides such as are found in cough medicines and expectorants. This case report is unique in that pustular iododerma followed wound irrigation with 10% povidone-iodine.

Report of a Case  A 57-year-old man complained of a generalized pustular eruption. He had bilateral wound abscesses in the groin from a six-month-old aortal bifemoral bypass. The wounds had been incised, drained, debrided, and irrigated with 10% povidone-iodine at the rate of 100 ml/hr via intracatheters for 24 hours. The patient also began receiving oxacillin and chloramphenicol one day before the debridement.Twenty-four hours after debridement, numerous 2- to 4-mm pustules on an erythematous base appeared on the arms, face, and thighs. The lesions were especially numerous on the eyelids and beneath a