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March 15, 1971

Mumps With Orchitis And Lymphosarcoma

Author Affiliations

Savannah, Ga

JAMA. 1971;215(11):1827. doi:10.1001/jama.1971.03180240075028

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To the Editor.—  Patients with malignant lymphoma exhibit increased susceptibility to herpes zoster and to other kinds of infections. Relationship between infectious mononucleosis, the Epstein Barr virus, and the lymphomas has been much written about in recent years. Cases of well-documented infectious mononucleosis have occurred in patients with leukemia and lymphoma in remission. In light of this, a recent case seen by us seems of more than passing.

Report of a Case.—  A 41-year-old railroad worker suffered from a duodenal ulcer in 1964, treated by gastric freezing, and in 1965, by gastrectomy. The gastrectomy specimen showed lymphosarcoma of a small-cell-type.Within the year tumors of his parotid gland were biopsied and thought initially to be benign lymphoepithelioma. He went on however to develop pulmonary lesions and an open lung biopsy in March 1969, which showed lymphosarcoma of the lung. Subsequently cobalt 60 therapy to the left lung and later to