Doxepin hydrochloride may be effective in the treatment of symptoms of depression with or without accompanying anxiety in patients with neurotic or psychotic disorders. The incidence and severity of its adverse reactions are similar to those of other tricyclic antidepressant drugs.
Evaluation of Doxepin Hydrochloride(Sinequan). JAMA. 1971;215(12):1967–1968. doi:10.1001/jama.1971.03180250059015