One hundred forty-seven consecutive patients scheduled to undergo coronary angiography were classified according to the type-A behavior pattern. Statistically significant correlations were found between disease severity and the physical risk factors cholesterol, smoking, hypertension, sex, and age. The correlation of the behavior pattern with angiographic disease severity was of the same magnitude as that of the other risk factors except cholesterol, which was greater. The association between the behavior pattern and severity persisted after adjustments had been made for the effects of five other major risk factors.
(JAMA 240:761-763, 1978)
Frank KA, Heller SS, Kornfeld DS, Sporn AA, Weiss MB. Type A Behavior Pattern and Coronary Angiographic Findings. JAMA. 1978;240(8):761–763. doi:10.1001/jama.1978.03290080051026
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