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August 21, 1981

Biochemistry of Nonheme Iron

Author Affiliations

University of Washington School of Medicine Seattle

JAMA. 1981;246(8):896. doi:10.1001/jama.1981.03320080076044

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This book represents somewhat of a tour de force for a single author in the scope of literature reviewed. It contains nine chapters, all but one by Bezkorovainy: "Tissue Iron and an Overview on Nonheme Iron Biochemistry," "Ferrokinetics," "Absorption of Nonheme Iron" (by Doris Narins), "Chemistry and Metabolism of Transferrins," "Chemistry and Biology of Iron Storage," "The Interaction of Nonheme Iron With Immature Red Cells," "Microbial Iron Uptake and Antimicrobial Properties of the Transferrins," "Iron Sulfur Proteins," and "Miscellaneous Aspects of Iron Metabolism." Each chapter begins with biochemical background, discusses contemporary work, and ends with an extensive reference section. The 435 pages provide a comprehensive review of the biochemistry and physiological behavior of the iron-binding proteins, including the often neglected iron sulfur proteins.

In addition to numerous typographical mistakes, there are certain limitations to the way the material is handled. The book is inclusive, rather than critical, and outdated concepts