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August 21, 1981

The Neurocristopathies

JAMA. 1981;246(8):896. doi:10.1001/jama.1981.03320080076045

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Although the cells of the neural crest migrate to almost every part of the body, they maintain similar morphological, chemical, functional, and biologic characteristics. Assembly of diseases of these cells into a concise monograph of related disorders could be of great help in understanding the problems of patients so affected. It would encourage the development of concepts and result in the correlation of an even greater variety of syndromes whose interrelationships have gone unrecognized.

A 233-page text that attempts all this, in addition to a description of the embryologic development of the neural crest and its derivatives, requires organization, clarity, conciseness, and completeness. It is unfortunate that these essentials have not been achieved in this monograph. The translation from the original French appears to have been done by a nonphysician who has introduced terminology not of general medical usage. In addition, many sentences are convoluted, with errors in structure and