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November 24, 1978

Abdominal Epilepsy: A Cause of Abdominal Pain in Adults

Author Affiliations

From the Departments of Medicine (Dr Peppercorn) and Neurology (Drs Herzog, Dichter, and Mayman), Harvard Medical School, Thorndike Laboratories at the Beth Israel Hospital, Boston.

JAMA. 1978;240(22):2450-2451. doi:10.1001/jama.1978.03290220062018

Four patients, aged 17 to 47 years, had paroxysmal abdominal pain associated with symptoms suggestive of a CNS disturbance. None had a discernible primary gastrointestinal process, but each had EEG abnormalities and a striking response to anticonvulsant medication. These findings suggest that abdominal epilepsy should be considered in the differential diagnosis of unexplained paroxysmal abdominal pain.

(JAMA 240:2450-2451, 1978)