[Skip to Content]
[Skip to Content Landing]
November 24, 1978

Recognition of Impending Ketoacidosis Delayed by Ketone Reagent Strip Failure

Author Affiliations

From the North Florida Regional Diabetes Program (Dr Rosenbloom) and the Suncoast Regional Diabetes Program (Dr Malone), Children's Medical Services Program, Department of Health and Rehabilitative Services of the State of Florida; the Division of Endocrinology (Dr Rosenbloom), Department of Pediatrics, University of Florida, Gainesville; and the Division of Metabolism (Dr Malone), Department of Pediatrics, University of South Florida, Tampa.

JAMA. 1978;240(22):2462-2464. doi:10.1001/jama.1978.03290220074023

During a one-year period, six patients were admitted to the hospital in diabetic ketoacidosis following 12 to 24 hours of illness at home. Urine testing with strips impregnated with sodium nitroprusside had indicated that no ketone bodies were present. Nine of 11 bottles of reagent strips in use for less than three months by these and other patients contained totally unreactive strips. Nitroprusside tablets exposed more than three months continued to give accurate readings.

(JAMA 240:2462-2464, 1978)