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December 1, 1978

Treatment of Hypertension-Reply

Author Affiliations

Editorial Review and Publications Subcommittee Hypertension Detection and Follow-up Program Cooperative Group University of California, Davis Davis

JAMA. 1978;240(23):2541-2542. doi:10.1001/jama.1978.03290230033015

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The Hypertension Detection and Follow-up Program (HDFP) is a multicenter cooperative effort designed to determine the effectiveness of systematic and sustained antihypertensive thereapy in reducing mortality in a wide spectrum of persons with elevated BP. The effort was initiated by the National Heart, Lung, and Blood Institute based on the following three major findings:

  1. Prospective epidemiologic studies that showed persons with elevated BP are noticeably at high risk of cardiovascular disease mortality.

  2. The results of clinical trials that showed pharmacologic treatment of high BP is efficacious for middle-aged men with average diastolic BP greater than 105 mm Hg.

  3. Population surveys that demonstrated a poor control situation with less than 15% of all hypertensive persons detected and effectively treated. Thus, the HDFP has been investigating two specific questions: (a) In defined populations of different socioeconomic and ethnic composition, is it possible to detect the suspect hypertensive