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We do not oppose the performance of both an oral cholecystogram and an upper GI series in patients regarding whom differentiation between diseases involving the two systems is difficult. We would never suggest that a patient with classic peptic ulcer symptoms and gallstones not have a GI series.
We did not conclude that a GI series is unnecessary in patients with gallstones. What we did was examine the films of 100 patients defined in a particular way and demonstrate a potentially important abnormality by upper GI series in only four of them. In our patients, the GI series had a relatively low yield of identifying abnormalities in patients with gallstones in the absence of GI bleeding or suspicion of GI cancer.
Leonard MH, Schreiber MH. Gastrointestinal Series in Patients With Gallstones-Reply. JAMA. 1978;240(25):2734. doi:10.1001/jama.1978.03290250038020
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