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December 15, 1978

Prognostic Importance of Pruritus in Hodgkin's Disease

Author Affiliations

From the Hematology/Oncology Division, Denver Veterans Administration Hospital (Drs Mahmood and Wallner), and the Hematology/Oncology Division, University of Colorado Medical Center (Dr Feiner), Denver.

JAMA. 1978;240(25):2738-2740. doi:10.1001/jama.1978.03290250042025

In 1971 participants in the Ann Arbor Conference on Hodgkin's disease thought that pruritus had no independent prognostic importance. We reviewed our series of patients with Hodgkin's disease and found six patients in whom severe itching was a major clinical problem. When compared with similarly treated patients without pruritus, these patients appeared to have more-aggressive disease. Severe itching, alone or with B symptoms, needs further study, since it may presage a poor prognosis.

(JAMA 240:2738-2740, 1978)