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December 15, 1978

Pathology of the Spinal Cord

Author Affiliations

University of Illinois Chicago

JAMA. 1978;240(25):2777. doi:10.1001/jama.1978.03290250081044

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The object of the author has been to provide "a concise textbook of diseases and traumas affecting the human spinal cord" in a series to which he also contributed a volume on pathology of muscle. The limited number of responses of the cells of the CNS to disease appear in the introduction, followed by description of normal and abnormal development and congenital disorders.

Degeneration of various anatomic patterns of neurons and their prolongations are treated separately from demyelinating, toxic, and deficiency diseases. The section on tumors is indeed concise and somewhat limited, so that the reported difference between schwannoma and neurofibroma is not illustrated, and hemangioblastoma is allotted two lines (and omitted from the index). There are almost equal amounts on pathogenesis and on actual histological description of trauma to the spinal cord; this is a field of much interest to Hughes, whose close association with the National Spine Injuries