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Article
January 26, 1994

Metered-Dose Inhalers: Mouth Open or Closed?-Reply

JAMA. 1994;271(4):272-273. doi:10.1001/jama.1994.03510280034024
Abstract

In Reply.  —We agree with Dr Newman that the open-mouth or spacer technique is an effective method of using an MDI; however, we disagree with the description of the closed-mouth technique as being incorrect.In a review of MDIs in asthma treatment, Tinkelman et al1 stated that both open- and closed-mouth techniques have

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