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I welcome the opportunity to respond to the comments of Drs Odio and Eaton.Dr Odio's primary concern appears to be my failure to address the problem of differentiating individuals who have streptococcal pharyngitis from those who are chronic streptococcal carriers. These and other issues mentioned in his letter are important problems, but it was not my intention to cover all aspects of and issues relevant to streptococcal pharyngitis. As implied in the title and stated in the beginning of the review, my intention was to "focus on the landmark studies and developments that have been major contributions in helping us arrive at what we now believe is the optimal antimicrobial treatment of this disease."Dr Odio points out that the three recently published studies I referenced—which now confirm that early treatment of streptococcal pharyngitis can reduce the duration of symptoms to less than 24 hours in most
James W. Bass. The Treatment of Streptococcal Pharyngitis-Reply. JAMA. 1987;257(2):187. doi:10.1001/jama.1987.03390020052015
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