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November 6, 1981

Percutaneous Transluminal Angioplasty for the Treatment of Renovascular Hypertension

Author Affiliations

From the Departments of Radiology (Drs Tegtmeyer and Brown), Internal Medicine (Dr Ayers), and Surgery (Dr Wellons), the University of Virginia School of Medicine and Medical Center, Charlottesville, and the Department of Radiology, Fairfax Hospital, Fairfax, Va (Dr Stanton).

JAMA. 1981;246(18):2068-2070. doi:10.1001/jama.1981.03320180060036

PHARMACOTHERAPY and surgical revascularization are the two treatment modalities widely available for the management of renovascular hypertension. Both methods of treatment are successfully used in the treatment of renovascular disease in selected patients, but neither method is ideal.

A third method of treating renovascular disease, percutaneous transluminal angioplasty (PTA), is presently undergoing extensive evaluation. Percutaneous transluminal angioplasty was developed originally for the treatment of atherosclerotic peripheral vascular disease.1 The development of the soft, flexible, doublelumen Grüntzig balloon catheter,2 however, has allowed the procedure to be applied to the renal arteries. Renovascular hypertension caused by atherosclerotic narrowing of the renal arteries has been successfully treated.3,4 Furthermore, the technique has been utilized successfully to treat patients with renovascular hypertension secondary to fibromuscular dysplasia.5-7

The techniques, results, and versatility of PTA of renal arteries are described.

Report of Cases 

Case 1.—  A 24-year-old woman was admitted with a two-year