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January 23, 1987

Neonatal Herpes Simplex Virus Infection Occurring in Second Twin of an Asymptomatic MotherFailure of a Modern Protocol

JAMA. 1987;257(4):508-511. doi:10.1001/jama.1987.03390040124030

A case of neonatal herpes that occurred after vaginal delivery in the absence of genital lesions is presented. The mother had a history of drug addiction and genital herpes. Asymptomatic shedding of herpes simplex virus type 2 from the cervix was noted in the second trimester of pregnancy. Despite being followed with a protocol of close surveillance and serial culturing of the genital tract, the patient gave birth to twins, one of whom developed herpes simplex virus type 2 in the postpartum period. This report presents discussion of this case and herpes surveillance protocols.

(JAMA 1987;257:508-511)