Significant advances in diagnosis and management of tricyclic antidepressant overdose have occurred in recent years. This article reviews epidemiologic, pharmacologic, and therapeutic information to provide a systematic approach to these potentially life-threatening overdoses. The tricyclics are discussed as a group, with individual drugs specified when established differences exist.
Frommer DA, Kulig KW, Marx JA, Rumack B. Tricyclic Antidepressant OverdoseA Review. JAMA. 1987;257(4):521–526. doi:10.1001/jama.1987.03390040137034
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