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November 27, 1981

Outcome of Renal Transplantation for End-Stage Reflux Nephropathy

Author Affiliations

Mayo Clinic Rochester, Minn

JAMA. 1981;246(21):2430. doi:10.1001/jama.1981.03320210012006

To the Editor.—  In a recent editorial (1981;245:2430), Samuel Vaisrub, MD, compared two retrospective studies1,2 describing the progression of reflux nephropathy. Dr Vaisrub's comment on the discrepancy of these studies regarding the outcome of renal transplantation is inaccurate. Our article did not contain any information on the results of renal transplantation in our patients. The reason for Dr Vaisrub's comments on this subject is unclear to us. We think that these comments may be misleading.Indeed, the unpublished experience of our renal transplantation team is in good agreement with that reported by Bhathena et al.2 Forty-eight patients with end-stage reflux nephropathy have received 55 renal allografts at the Mayo Clinic from 1968 to 1980. Ureteroneocystostomies of the transplanted ureters were done, using an antireflux technique. At present, 33 renal allografts are functioning satisfactorily. Two patients have died of unrelated causes with normal allograft function. Fifteen allografts were lost

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