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January 8, 1982

The Patient With Multiple Alloantibodies: One Possible Answer to Meeting Blood Needs

JAMA. 1982;247(2):209. doi:10.1001/jama.1982.03320270047024

PATIENTS with multiple alloantibodies pose a problem when they require transfusions. Blood may be obtained from a rare donor file if the specificities of the antibodies are known. Under certain circumstances the recipient may be able to serve as his own donor. We describe here a patient who, because of traumatic cardiac hemolytic anemia, was not a candidate for autologous transfusion and had only one available compatible donor. Ten units of blood were collected from this donor during a 17-week period so that the patient might have her dysfunctional aortic valve prosthesis replaced.

Report of a Case  The patient, a 32-year-old woman, gravida 2, para 2, underwent aortic valve replacement with a cloth-covered Starr-Edwards prosthesis in 1974 for acute bacterial endocarditis. During the surgery she received 5 units of whole blood. She was transfused again in 1976 (3 units of RBCs) and in 1978 (4 units of RBCs) for anemia