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January 15, 1982

Intravenous Potassium Chloride Therapy

JAMA. 1982;247(3):304. doi:10.1001/jama.1982.03320280026015

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To the Editor.—  Some comment is prompted by a QUESTIONS AND ANSWERS article (1981;245:2446) concerning intravenous potassium chloride therapy. I would be interested to know if Drs DeFronzo and Bia meant to write that they "have had to infuse as much as 80 to 100 mEq/L during one hour to suppress the ventricular irritability" and that such was done "by using two peripheral IVs containing 40 to 50 mEq/L infused during one hour," thereby administering a total volume load of 2 L in one hour? That is quite a volume load for a heart with ventricular irritability.