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June 19, 1987

Corneal Perforation Caused by Dysgonic Fermenter—2

JAMA. 1987;257(23):3269-3270. doi:10.1001/jama.1987.03390230105035

DYSGONIC fermenter—2 (DF-2) is the Centers for Disease Control designation given to a fastidious gram-negative organism that causes cellulitis, septicemia, meningitis, and endocarditis in man.1-9 Infections with this agent are frequently associated with dog contact or dog bite, and DF-2 has been shown to be a member of the oral flora of dogs.10 This organism is oxidase positive, catalase positive, and urease negative and does not grow on MacConkey's agar. Infection with this agent occurs preponderantly in debilitated patients and in patients with splenectomy. To date, to our knowledge, there has been no report of ocular infection with DF-2. We report the case of a man with severe corneal necrosis in which DF-2 was the only organism isolated and the patient's subsequent response to surgical débridement and treatment with ceftizoxime sodium.

Report of a Case  A 62-year-old man was seen at the Kresge Eye Clinic of Wayne State