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January 15, 1982

Antithrombin III Level in Nonatherosclerotic Vasculopathy

JAMA. 1982;247(3):305. doi:10.1001/jama.1982.03320280027021

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To the Editor.—  Regarding a recent BRIEF REPORT, "Intra-arterial Alprostadil for Nonatherosclerotic Vasculopathy" (1981;245:1846), there is no mention of antithrombin III levels. In a patient in this age group with a history of venous thromboembolism, who on angiography has evidence of multiple arterial occlusions, I think it would be important to rule out antithrombin III deficiency as a possible cause, as this condition may be treatable with long-term warfarin sodium therapy.