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January 22, 1982

Pediatric CVAs linked to lipid abnormalities

JAMA. 1982;247(4):418. doi:10.1001/jama.1982.03320290004002

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The child was scarcely more than a baby. Yet, at the age of 17 months, she had suffered a stroke that left residual weakness on her right side. However, for University of Cincinnati physicians, the real surprise involved the child's mother.

This 28-year old woman also had suffered a stroke while a child. Hers had occurred when she was 7 years old, and apparently she had recovered completely.

Cerebrovascular accidents in children are among the most tragic and puzzling problems in pediatrics, so this familial occurrence sent Charles J. Glueck, MD, and colleagues to the medical records in the hope of piecing together at least part of the puzzle.

Their conclusion, as reported at the American Heart Association meeting in Dallas, is that familial lipoprotein abnormalities appear to be involved. These abnormalities, they suggest, may be related to "hundreds" of the childhood strokes that occur in this country every year.