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February 12, 1982

Carcinogen Regulation

JAMA. 1982;247(6):751. doi:10.1001/jama.1982.03320310015003

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To the Editor.—  I agree with much of what was written in the article entitled "Carcinogen Regulation" (1981; 246:253). On the same subject, may I recommend "Assessment of Technologies for Determining Cancer Risks From the Environment" (Office of Technology Assessment, June 1981), which strongly endorses the continued need for animal testing.One point requires clarification. The cost of long-term bioassays is estimated at between $250 and $750 million a year (100 to 300 a year times $250,000 per test). In fact, the total amount spent on long-term animal bioassays is considerably less. At the National Toxicology Program (NTP), where most of this testing is done in the federal government, we spend about $40 million. Because the NTP is including special studies (hematology, urinalysis, and assessments of damage to kidney, liver, lungs, and the immune and nervous systems), these broadened bioassays will provide scientists with more toxicological information than a simple