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December 21, 1979

Hemoglobin A1c in Normal and Diabetic Pregnancy

Author Affiliations

From the Division of Perinatal Medicine, Department of Obstetrics and Gynecology, Duke University Medical Center, Durham, NC. Dr Miller is now with the Department of Obstetrics and Gynecology, Medical University of South Carolina, Charleston.

JAMA. 1979;242(25):2785-2787. doi:10.1001/jama.1979.03300250041029

The usefulness of determining hemoglobin A1c (HbA1c) levels during pregnancy was evaluated. In contrast to previous reports, the HbA1c values did not predict abnormal maternal glucose tolerance or infant birth weight. They did, however, correlate with long-term control of the diabetes of pregnant insulin-dependent patients. The slight decrease in HbA1c values observed as pregnancy advanced was secondary to improved control of diabetes.

(JAMA 242:2785-2787, 1979)