EPIDERMOLYSIS bullosa acquisita (EBA) is a nonheritable, noninflammatory, subepidermal mechanobullous disease of adults, characterized by the appearance of cutaneous blisters and ulcers after minor trauma.1 Epidermolysis bullosa acquisita occurred in an elderly woman as the initial manifestation of amyloidosis and multiple myeloma.
Report of a Case
An 81-year-old woman was admitted to The Johns Hopkins Hospital with fractures of the left humerus and left femur and denuded areas of skin in both axillae and over the left hip. For two years before admission, the patient had experienced easy bruising and fragile skin. Cutaneous blisters formed after minimal skin trauma, and with mild trauma, patches of skin were completely avulsed. There had been no infections in the areas of injured skin, and they healed normally. There was no family history of skin disease.On the evening of admission, the patient had risen from bed and fallen to the floor. She experienced
Trump DL, Allen H, Olson J, Wright J, Humphrey RL. Epidermolysis Bullosa Acquisita: Association With Amyloidosis and Multiple Myeloma. JAMA. 1980;243(14):1461–1462. doi:10.1001/jama.1980.03300400045031
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