It has been estimated that each year more than 1 million Americans will be given diagnoses of cancer. The mortality from cancer, however, has decreased, particularly for persons younger than 30 years, but even among those younger than 45 years. Thus, the proportion of patients being cared for with a diagnosis of malignant disease continues to increase as a direct result of improved palliative therapy and a clear increase in the proportion of patients who are fully cured. This latter group has now been shown to have, among other medical problems, an enhanced risk of the development of a secondary malignant neoplasm.1
The past decade has witnessed rapid advances in methods for early detection of cancer: xeromammography, computerized tomographic scanning, ultrasound, and tumor markers are only a few. In addition, of value to cancer prevention is the growing information on the association of carcinogenesis with the use of tobacco,
Freireich EJ. Oncology. JAMA. 1980;243(21):2199–2201. doi:10.1001/jama.1980.03300470059034
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