Minoxidil is a potent, long-acting, orally effective vasodilator that recently became available for general use in the United States. It is given with a diuretic and a β-blocking drug to treat severe hypertension that cannot be controlled by conventional therapy. Fluid retention and hypertrichosis are the most common adverse reactions.
(JAMA 244:73-75, 1980)
Kosman ME. Evaluation of a New Antihypertensive Agent: Minoxidil. JAMA. 1980;244(1):73–75. doi:10.1001/jama.1980.03310010059037
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