[Skip to Content]
Access to paid content on this site is currently suspended due to excessive activity being detected from your IP address Please contact the publisher to request reinstatement.
[Skip to Content Landing]
April 9, 1982

Medical Pharmacology: Principles and Concepts

Author Affiliations

Tufts-New England Medical Center Boston


by Andres Goth, ed 10; 815 pp, 112 illus, $28, St Louis, CV Mosby Co, 1981.

JAMA. 1982;247(14):2027. doi:10.1001/jama.1982.03320390085059

This article is only available in the PDF format. Download the PDF to view the article, as well as its associated figures and tables.


A generation of medical students owes its survival to Andres Goth. Now in its 20th year and tenth edition, Goth's Medical Pharmacology has rendered intelligible and tolerable the often alien and all too quantitative discipline of pharmacology, firmly sealing its link with clinical medicine. Over the years Goth has retained this flavor and, with it, an immense popularity. Yet Goth has changed substantially with the times, keeping up in the past two decades with the almost complete turnover of pharmacology, from a descriptive, observational science into a staggering technocracy of molecular biology, receptor theory, pharmacodynamic quantitation, and pharmacokinetic modeling.

After two topical sections dealing with general aspects of pharmacology and drug effects of neurotransmitters, the next seven are organsystem- and disease-oriented in the classic sense. Three newer topics appearing in recent editions include immunopharmacology, drug interactions, and poisons-antidotes. Another relatively new feature consists of reference appendices on blood concentrations of