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April 16, 1982

Thermic Stress Syndrome

JAMA. 1982;247(15):2098-2099. doi:10.1001/jama.1982.03320400018018

To the Editor.—  The letter by James D. Lydiatt, MD, and Gary E. Hill, MD, entitled "Treatment of Heat Stroke by Dantrolene" (1981;246:41), again emphasizes that "heat stroke" and "malignant hyperthermia" may be identical conditions with different triggering mechanisms that respond to the same treatment. Other variations of thermic stress syndrome are "sudden death syndrome in athletes," "idiopathic recurrent rhabdomyolysis with myoglobinuria," "exercise myohemoglobinuria," "fulminant hyperthermic porcine stress syndrome" and "neuroleptic malignant syndrome."Each of these syndromes has been described in the literature with scant recognition that other authors, using different titles, have described what seems to be the same malady. Measures used for successful treatment of fulminant hyperthermic porcine stress syndrome, malignant hyperthermia, and heat stroke appear to be the same.1 In 1973, Meltzer2 discussed the similarities between the neuroleptic malignant syndrome and malignant hyperpyrexia. Probably, treatment will prove to be the same.These thermic stress syndromes