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May 7, 1982

Single-lung transplants to resume soon with cyclosporin A therapy

JAMA. 1982;247(17):2331-2332. doi:10.1001/jama.1982.03320420005001

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The first human single-lung transplant in which cyclosporin A is used as an immunosuppressive agent probably will be performed sometime this year. The likely surgeon? Frank J. Veith, MD, chief of vascular surgery and director of the transplant program at Montefiore Hospital and Medical Center, Bronx, NY, who attempted five lung transplants between 1969 and 1973.

In a recent interview with JAMA MEDICAL NEWS, Veith conceded that his team is ready and in effect has the green light from the Food and Drug Administration and Sandoz, Inc, maker of cyclosporin A. However, he added: "I think we'll have to wait at least six months to get a suitable donor."

Thirty-eight human single-lung transplants were attempted between June 11, 1963, when James D. Hardy, MD, performed the first one, and May 13, 1977, when a team from the University of Toronto performed the last reported one. All 38 were performed before cyclosporin