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October 10, 1980

A Familial Pattern of Thyroglossal Duct Cysts

JAMA. 1980;244(15):1714. doi:10.1001/jama.1980.03310150050033

CONGENITAL lesions make up about 6% of all masses found within the neck.1 Approximately two thirds of these congenital abnormalities involve the thyroglossal duct in the form of cysts or sinuses. Despite the frequent occurrence of thyroglossal duct malformations, a familial pattern, to our knowledge, has not been described.

Report of a Case  A healthy 1-year-old girl was admitted to the Denver General Hospital with a painless, midline cervical mass over the hyoid bone. There was no history of airway or feeding problems and no symptoms of any endocrine disorder. The family history was remarkable for hypothyroidism, thyroid carcinoma, and thyroglossal duct defects (Figure).Physical examination disclosed a 1×1-cm, nontender cervical mass located in the midline at the level of the hyoid bone. No cutaneous fistulous tract was noted.These findings were suggestive of a thyroglossal duct cyst. Surgical excision, using the Sistrunk technique,2 demonstrated a squamous cell-lined