We evaluated 1,266 persons who had received external radiotherapy for benign diseases in childhood. The evaluation used detailed questionnaires completed by trained interviewers and neoplastic disease registry data. The control population included 958 age-, sex-, race-, and diseasematched persons who had not received radiotherapy and 9,865 family members of the two study groups. An excess number of clinically important thyroid neoplasms, both benign and malignant, was noted in the irradiated group.
(JAMA 244:1802-1805, 1980)
Maxon HR, Saenger EL, Thomas SR, et al. Clinically Important Radiation-Associated Thyroid Disease: A Controlled Study. JAMA. 1980;244(16):1802–1805. doi:10.1001/jama.1980.03310160018016
Browse and subscribe to JAMA Network podcasts!
Customize your JAMA Network experience by selecting one or more topics from the list below.
Create a personal account or sign in to: