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October 17, 1980

Heparin Necrosis: An Anticoagulation Syndrome

Author Affiliations

From the Sections of Dermatology (Dr Hall), Pathology (Dr Gibson), and Cardiology (Drs McConahay, Crockett, and Conn), St Luke's Hospital, Kansas City, Mo.

JAMA. 1980;244(16):1831-1832. doi:10.1001/jama.1980.03310160047027

Lesions indistinguishable from coumarin necrosis developed in three patients who were given heparin sodium subcutaneously. Two of the patients had received only heparin while another had also received coumarin. Heparin necrosis should be added to the list of complications of anticoagulation therapy.

(JAMA 244:1831-1832, 1980)