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October 17, 1980

The Role of Radiation Therapy in Endometrial Cancer

Author Affiliations

From the Department of Radiation Therapy, Medical College of Wisconsin, Milwaukee.

JAMA. 1980;244(16):1837-1839. doi:10.1001/jama.1980.03310160051030

RECENT emergence of adenocarcinoma of the uterine corpus as the most common invasive gynecologic malignant neoplasm in the United States is attributable to several concurrent factors. Earlier detection of carcinomas of the uterine cervix, still in noninvasive stages, through widespread cytologic screening, is chief among these, but it also may be attributed to an absolute increase in the incidence of endometrial cancer noted during the past decade.1 Despite observations that these neoplasms may be undergoing transition to greater virulency, more than three fourths of patients continue to present with an early clinical stage of disease. Good results in treating these stages have been reported often but are not sufficiently satisfactory to justify the often complacent attitude of some therapists. In our aging population, with its reduced parity levels, and potential exposure to known or suspected carcinogens, it is essential to optimize available therapy.

The challenge presented by this increasingly