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Dr Elias Schwartz has done a masterful job in this monograph, which surveys and synthesizes the current knowledge and theory on hemoglobinopathies. Although this book is part of a pediatric series, it contains a wealth of general information useful to the internist, generalist, and adult hematologist alike. The monograph is exceptionally well edited and reads smoothly and consistently.
The book is divided into three major sections. Part 1, constituting about half of the book, is an in-depth review of the anatomy and physiology of hemoglobin at the molecular level. A 16-page table catalogues known hemoglobinopathies for ready reference and review. The chapter on methodology provides solid background information in addition to useful information on improving the separation and identification of hemoglobin variants. This reviewer found some of the morphological photographs to be overenlarged, lacking the crispness we are used to seeing via the microscope. They do, however, convey the essential
Seeler RA. Hemoglobinopathies in Children. JAMA. 1980;244(17):1981. doi:10.1001/jama.1980.03310170077043
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