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November 14, 1980

Acquired Immune Hemolytic Anemias

Author Affiliations

University of Chicago Medical Center

JAMA. 1980;244(19):2211. doi:10.1001/jama.1980.03310190061031

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The authors of this mongraph attempt the difficult task of combining in a single volume both the clinical and laboratory aspects of immunohematology needed for a comprehensive understanding of this subject. In so doing, they present a broad range of subject matter that varies in complexity from the most elementary definitions of clinical and laboratory terms—hemolytic anemia, Coombs' test—to state-of-the-art discussions of management of autoimmune hemolytic anemias and sophisticated autoanalyzer techniques for differentiation of types of antibody-RBC interactions.

The text is well organized and clearly written. It has excellent references at the end of each chapter and a good index. The original illustrations are generally well done, although there are occasional typographical inconsistencies between diagrams and text. The concise, illustrated reviews of the complement pathways, immunoglobulin structure and function, and the mechanisms of immune hemolysis are attractive as teaching references for related curricula. A full chapter is devoted to details