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May 14, 1982

Acquired Bleeding Disorders in Children, vol 3, Abnormalities of Hemostatis; vol 4, Platelet Abnormalities and Laboratory Methods

Author Affiliations

Cook County Hospital Chicago

JAMA. 1982;247(18):2595. doi:10.1001/jama.1982.03320430091044

This article is only available in the PDF format. Download the PDF to view the article, as well as its associated figures and tables.


Volume 3 of Acquired Bleeding Disorders in Children is a handy, compact, up-to-date reference on a wide variety of nonhereditary bleeding problems in children. It begins with one of the best available overviews of the interaction between platelets, plasma coagulation factors, and blood vessel endothelium. Individual chapters on a range of subjects follow, including hemorrhage in the new-born, disseminated intravascular coagulation, bleeding in acute leukemia, cyanotic congenital heart disease, and liver disease. The detailed chapter on hepatocellular disease and hemostasis with 202 references is possibly more scholarly than the general reader needs. Four subjects extensively covered by publications in internal medicine and the subspecialties that are not regularly seen by the pediatrician include bleeding in patients with renal failure, immune anticoagulants, antithrombin III, and the dangers of use of the prothrombin complex concentrates. These chapters present a nicely balanced clinical overview of their respective areas.

Volume 3 will have wide