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December 12, 1980

Gastrointestinal Hormones

Author Affiliations

Upstate Medical Center State University of New York Syracuse

JAMA. 1980;244(23):2671. doi:10.1001/jama.1980.03310230065035

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Most of the standard textbooks that deal with gastrointestinal (GI) hormones are relatively limited in scope and do not keep up with the rapid advances in this field. In contrast, the author of Gastrointestinal Hormones has achieved his objective of presenting a comprehensive, up-to-date, multiauthored review that covers the physiology, origin, chemistry, and pharmacologic and clinical aspects of the GI hormones.

The book is divided into seven distinct sections and contains 43 chapters, with little overlap between topics. The first section, on the cellular and neural origin of gut hormones, emphasizes morphology and methods for their study. The second section describes isolation, characterization, structure-activity relation, and biological function of the GI hormones and peptides, including secretin, gastrin, cholecystokinin, gastric inhibitory polypeptide, motilin, vasoactive intestinal peptide, pancreatic polypeptide, gut glucagonlike immunoreactants, action on the gut of peptides of amphibian skin, hormones acting on both brain and gut, and several other peptides.