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To the Editor.—
In their article, "Topical Agents Alone in Acne: A Blind Assessment Study" (243:1640, 1980), Swinyer and associates state, "The degree of surface dryness or brittleness in our study is the single variable significantly associated with failure to clear acne lesions (Table 2)." However, Table 2 actually indicates that patients with severe skin dryness showed more improvement than those with moderate skin dryness.The authors assert that their thesis regarding the usefulness of water avoidance in the treatment of acne is supported by their finding that a program of tretinoin, benzoyl peroxide, and water avoidance was as effective as a combination treatment of tretinoin and systemically given tetracycline. Since benzoyl peroxide (which is both an effective antiacne agent and extremely drying) was part of the water avoidance regimen, but not included in the non-water-avoidance regimen, this assertion is unjustified.Thus, the data presented by these authors do not
David A. Voron. Treatment of Acne. JAMA. 1981;245(1):30. doi:10.1001/jama.1981.03310260014009