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February 27, 1981

Preparation of the Vagina for SurgeryA Comparison of Povidone-Iodine and Saline Solution

JAMA. 1981;245(8):839-841. doi:10.1001/jama.1981.03310330029019

Patients undergoing major vaginal surgery and treated with prophylactic antibiotics were assigned to two groups in which the effectiveness of preoperative vaginal preparation with povidone-iodine was compared with that of saline solution. There was no difference in postoperative morbidity between the two groups, although a few more infections occurred in the group treated with povidone-iodine. It is suggested that simple dilution of the quantity of bacteria in the vagina is all that is essential for adequate preoperative vaginal preparation.

(JAMA 1981;245:839-841)