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May 1, 1981

Acute Aortic Thrombosis in Antithrombin III Deficiency

Author Affiliations

From the Department of Surgery, Beth Israel Hospital (Drs Shapiro and Salzman), the Departments of Medicine, Sidney Farber Cancer Institute (Dr Bauer), and the Harvard Medical School (Drs Shapiro, Bauer, and Salzman), Boston; and the Departments of Medicine and Cardiovascular Sur-; gery, Presbyterian Hospital, Pacific Medical Center, San Francisco (Dr Rodvien).

JAMA. 1981;245(17):1759-1761. doi:10.1001/jama.1981.03310420049031

Two cases of acute aortic thrombosis, a previously unreported complication of antithrombin III deficiency, are reported. Both patients had abnormally low antithrombin III levels, which improved to normal levels with warfarin sodium therapy. The possibility of antithrombin III deficiency should be considered in young patients with acute arterial thrombosis.

(JAMA 1981;245:1759-1761)