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June 25, 1982

Controversies in Oncology

JAMA. 1982;247(24):3364. doi:10.1001/jama.1982.03320490060048

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In 26 paired chapters, opposing views on 13 issues in medical oncology are presented. No attempt is made to be all inclusive (breast cancer, small cell lung cancer, and osteosarcoma are the only solid tumors covered), and the editor does not discuss the criteria used to select the subjects to be included. These range from the current and practical (combined radiation and chemotherapy for early Hodgkin's disease) to the well worn (efficacy of high-dose methotrexate) to the philosophical (euthanasia). Adjuvant radiation therapy for breast cancer and adjuvant chemotherapy for osteosarcoma and brain tumors are discussed. Adjuvant chemotherapy for breast cancer and issues in surgical oncology generally are omitted.

All of the authors use review article format, with heavy emphasis on reference to the current literature rather than a subjective synthesis of broader concepts. Most chapters are thoroughly referenced, and it is notable how often opposing authors draw different conclusions from