Of 671 children with acute otitis media seen in our private practice, only 23% had fever. Very high fever (≥40.5 °C) was noted in only two children. In only 4% of the 671 children did the fever last more than 48 hours after antibiotic treatment had been started. We found that the organism causing the acute otitis media was unrelated to the presence of fever associated with this illness.
Schwartz RH, Rodriguez WJ, Brook I, Grundfast KM. The Febrile Response in Acute Otitis Media. JAMA. 1981;245(20):2057–2058. doi:10.1001/jama.1981.03310450049023
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