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August 6, 1982

Huntington's Chorea

JAMA. 1982;248(5):599. doi:10.1001/jama.1982.03330050081054

This article is only available in the PDF format. Download the PDF to view the article, as well as its associated figures and tables.


Michael Hayden's book Huntington's Chorea (a deliberately different title than the current label of "Huntington's disease") is the first single-authored monograph available on the topic and is a remarkably accomplished discussion of this incurable disease. In contrast to previous multiauthored reviews of the best known of all dominantly inherited diseases, Hayden's monograph touches every aspect of recent research, emphasizes clinical data, and is blessed by smooth writing and skillful editing. The tables in particular are enlightening, with clear illustrations to convey both the social impact and the scientific facts.

Using his own collection and the extensive bibliography compiled by fellow members of the Committee on Huntington's Disease of the World Federation of Neurology, Hayden presents a broad historical and epidemiologic approach to the disease. The author's research in South Africa emphasized the relative rarity of the disease among Africans, and he details historical explanations of the worldwide geographic clusters of